Kakeru Shimoda Selected Research

purinoceptor P2Y6

11/2022	Redox-dependent internalization of the purinergic P2Y6 receptor limits colitis progression.
1/2020	Modulation of P2Y6R expression exacerbates pressure overload-induced cardiac remodeling in mice.
6/2017	Purinergic P2Y6 receptors: A new therapeutic target of age-dependent hypertension.

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Kakeru Shimoda Research Topics

Disease

3	Heart Failure 01/2020 - 01/2018
2	Cardiovascular Diseases (Cardiovascular Disease) 01/2019 - 06/2017
1	Colitis 11/2022
1	Weight Loss (Weight Reduction) 01/2019
1	Infarction (Infarctions) 11/2018
1	Hypoxia (Hypoxemia) 11/2018
1	Hypertrophy 01/2018
1	Cardiomegaly (Heart Hypertrophy) 01/2018
1	Vascular Remodeling 06/2017
1	Hypertension (High Blood Pressure) 06/2017

Drug/Important Bio-Agent (IBA)

3	purinoceptor P2Y6IBA 11/2022 - 06/2017
2	FilaminsIBA 01/2019 - 11/2018
1	Serine (L-Serine)FDA Link 11/2022
1	Cysteine (L-Cysteine)FDA Link 11/2022
1	UridineIBA 01/2020
1	Guanine Nucleotide Exchange Factors (Guanine Nucleotide Exchange Factor)IBA 01/2019
1	Dihydrotachysterol (AT 10)IBA 01/2019
1	Environmental Pollutants (Pollutants, Environmental)IBA 01/2019
1	cilnidipineIBA 11/2018
1	Adenosine Triphosphate (ATP)IBA 01/2018
1	NucleotidesIBA 01/2018
1	Purinergic Receptors (Receptors, Purine)IBA 01/2018
1	Endothelin-1 (Endothelin 1)IBA 01/2018
1	Angiotensin IIIBA 01/2018
1	LigandsIBA 01/2018
1	Adenosine (Adenocard)FDA LinkGeneric 01/2018
1	Clopidogrel (Plavix)FDA Link 06/2017
1	Pharmaceutical PreparationsIBA 06/2017
1	Uridine Diphosphate (UDP)IBA 06/2017
1	GTP-Binding Proteins (G-Protein)IBA 06/2017
1	Type 1 Angiotensin ReceptorIBA 06/2017